AI + Proteomics
Our work lies at the intersection of chemistry and biology, spanning diverse fields including chemical biology, biochemistry, computational biology, epigenetics and cancer biology. Our mission is to explore the complex cellular landscape, revealing insights into clinical markers and drug targets.
开源算法与预测平台：CIMAGE2.0、CHiMA、SESTAR++，助力蛋白质组学数据分析。
We are looking for motivated PhD students and Postdocs.
gaojinjun#pku.edu.cn
Office
Room 210, Building F-East
Institution
PKUSZ · SCBB
Principal Investigator
Assistant Professor
Dr. Gao is a tenure-track assistant professor and principal investigator at the School of Chemical Biology & Biotechnology, Peking University Shenzhen Graduate School. He specializes in chemoproteomics and computational proteomics. During his Ph.D. at Peking University, he developed several innovative methods including SESTAR, CIMAGE, and rdTOP-ABPP.
Following his Ph.D., Dr. Gao pursued postdoctoral training at The University of Chicago. His research clarified that the predominant form of lactylation is L-lactylation, a discovery important for the lactylation field and a potential hypoxia biomarker. His work has been featured in Nature, Nature Chemical Biology, PNAS, and ACS Central Science.
Research Interests
Education
Postdoctoral Fellow
The University of Chicago
2019 – 2024
Ph.D. in Chemical Biology
Peking University
2013 – 2019
Our Team
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张嘉艺
Admin Assistant
2536199055#pku.edu.cn
_members.jpg)
董沫辰
Postdoc · 2025
dongm#pku.edu.cn
_members.jpg)
高敏莉
Postdoc · 2025
1578617167#qq.com
_members.jpg)
江凯雯
Ph.D. · 2023
2301111354#stu.pku.edu.cn
_members.jpg)
李蕊
Ph.D. · 2024
2401111353#stu.pku.edu.cn
_members.jpg)
王元昊
Ph.D. · 2025
yuanhaowang25#stu.pku.edu.cn
_members.jpg)
陈涵宇
Ph.D. · 2025
2501111376#stu.pku.edu.cn
_members.png)
郭宇迪
Master · 2025
yudiguo25#stu.pku.edu.cn
_members.jpg)
李彤
RA · 2024
liilitong#163.com
_members.jpg)
卢颖
RA · 2024
luying1#pku.edu.cn
_members.jpg)
戎子昕
RA · 2024
zixin.rong#outlook.com
_memebers.jpg)
苗瑞
RA · 2025
ruimiao#pku.edu.cn
_members.jpg)
葛金宝
RA · 2025
gejinbao#pku.edu.cn
Our vision
We focus on advancing proteomic technologies to unlock deeper insights into protein post-translational modifications (PTMs). By combining cutting-edge chemical tools with AI, we explore cellular mechanisms to identify next-generation biomarkers and drug targets.
Developing AI platforms to discover and predict novel post-translational modifications of proteins at scale.
Focusing on lysine lactylation and targeting lactylation pathways for cancers and neurodegenerative diseases.
Exploring disease markers and drug targets through AI-enhanced clinical proteomics toward precision medicine.
Systematic Approach
Selected Works
(# co-first author, * corresponding author)
Jinjun Gao, Ruilong Liu, Kasturi Chakraborty, Xinlei Sheng, Chang Han, Lev Becker, Yingming Zhao*.
Di Zhang*, Jinjun Gao#, Zhijun Zhu, Qianying Mao, Zhiqiang Xu, et al., Yingming Zhao*.
Jinjun Gao, Xinlei Sheng, Jianfeng Du, Di Zhang, Chang Han, Yue Chen, Chu Wang*, Yingming Zhao*.
Jinjun Gao#, Fan Yang#, Jinteng Che, Yu Han, Yankun Wang, Nan Chen, Daniel W. Bak, Shuchang Lai, Xiao Xie, Eranthie Weerapana, Chu Wang*.
Huairui Yuan, Xujia Wu, ... Jinjun Gao, et al., Jeremy Rich*.
Nature. 2023.
Carlos Moreno-Yruela#, Di Zhang#, Wei Wei, Michael Bæk, Jinjun Gao, et al., Yingming Zhao*.
Science Advances. 2022. 8:eabi6696.
Ziad Ibrahim, ... Jinjun Gao, et al., Daniel Panne*.
Nature Communications. 2022. 13:7759.
Huan Tang#, Guogeng Jia#, Jinjun Gao, Fan Yang, Ziyao Tang, Yuan Liu, Chu Wang*.
Analytical Chemistry. 2022, 94, 27, 9636–9647.
Guogeng Jia, Jinjun Gao, Fan Yang, Tianyu Feng, Chu Wang*.
Methods in Enzymology. 2022. 662:241–258.
Jinjun Gao#, Yuan Liu#, Fan Yang, Xuemin Chen, Benjamin F. Cravatt, Chu Wang*.
Journal of Proteome Research. 2021.
Kyle Delaney, Minjia Tan, Zhesi Zhu, Jinjun Gao, Lunzhi Dai, et al., Yingming Zhao*.
Cell Discovery. 2021. 7(1):122.
Fan Yang#, Jinjun Gao#, Jinteng Che, Guogeng Jia, Chu Wang*.
Analytical Chemistry. 2018. 90:9576–9582.
Daniel W. Bak*, Jinjun Gao, Chu Wang, Eranthie Weerapana*.
Cell Chemical Biology. 2018.
Ke Qin#, Yuntao Zhu#, Wei Qin, Jinjun Gao, Xuan Shao, et al., Xing Chen*.
ACS Chemical Biology. 2018, 13, 1983–1989.
Ying Chen, Yuan Liu, Tong Lan, Wei Qin, Yuntao Zhu, Ke Qin, Jinjun Gao, et al., Chu Wang*.
Journal of the American Chemical Society. 2018.
Jinjun Gao, Xinxin Yu, Fengming Ma, Jing Li.
PLOS ONE. 2014. 9:e88804.
Xinxin Yu, Jinjun Gao, Yong Li, Jing Li*.
China Biotechnology. 2014, 34:30–38.
Computational Resources
Expanded tool for quantitative analysis of activity-based probe profiling (ABPP) data.
Tailored database search strategy for comprehensive histone mark analysis.
Targeted proteomics using selenium's unique isotope distribution to identify low-abundance peptides with high sensitivity.
Upgraded SESTAR with a user-friendly GUI and a simple guide for data interpretation.
Opportunities
应聘者请将详细个人简历及其他能证明科研能力的相关电子文件合并为 1 个 PDF 发送至 gaojinjun#pku.edu.cn。博士后应聘额外提供 2 位推荐人的联系方式。邮件标题请注明"应聘岗位 + 姓名"。本招聘长期有效。
Please send your CV and supporting documents as a single PDF to gaojinjun#pku.edu.cn. Postdoc applicants should additionally provide contact information for 2 references. Please indicate "Position + Name" in the subject line. This position remains open until filled.
应聘条件
岗位待遇
应聘条件
岗位待遇
Why Join Us?
Your Role Matters
Work Collaboratively
Small Lab, Big Community
Integrated with Peking University, Key Laboratory of Chemical Oncogenomics, and Shenzhen Biological Medicine Promotion Association.
Location
Peking University
Shenzhen Graduate School
Shenzhen, China